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Elissaios Karageorgiou, MD, PhD

Scientific Director, NIA

Division Chief, Sleep & Memory Center​

Contact Info
phone: +30 210 7217 457​
clinic email:
personal email:
Biographical summary

Dr. Karageorgiou was born in Glasgow, Scotland, and raised in Athens, Greece, where he graduated from Athens College and subsequently obtained his MD and PhD degrees from the National and Kapodistrian University of Athens. Upon completion of his medical studies, he worked as a post-doctoral associate at the Brain Sciences Center of the University of Minnesota under the mentorship of Apostolos P. Georgopoulos, MD, PhD, studying the encephalographic brain patterns in health and diseases such as Alzheimer’s disease, multiple sclerosis, and schizophrenia. He subsequently completed residency training in Neurology at the University of Minnesota, where he also served as the Associate Chief Resident for Research and Education. After his residency, he joined the Memory and Aging Center at the University of California San Francisco where he completed a Behavioral Neurology fellowship and an Atlantic Institute fellowship for Equity in Brain Health. He further completed a Sleep Medicine fellowship at Stanford Sleep Medicine Center, towards obtaining comprehensive expertise in the fields of sleep and neurocognitive disorders. He has served as Assistant Professor in Neurology at UCSF before returning to his native Greece and establishing the Sleep & Memory Center at the Neurological Institute of Athens, combining his clinical practice in helping patients with sleep problems and cognitive impairment with his research in the field of Cognitive Behavioral Sleep Medicine.​

Dr. Karageorgiou’s primary goal is the provision of optimal care to his patients and their families, a goal which also guides his translational research. He has been awarded the Robert Katzman, MD, Clinical Research Training Fellowship by the American Brain Foundation and the Alzheimer’s Association for studying encephalographic patterns of neurodegenerative diseases and the Young Investigator Award by the International Congress on Schizophrenia Research for his work on the early diagnosis of schizophrenia and related psychoses. During his residency at the University of Minnesota, he received the John R. Gates Award for his clinical qualities and patient advocacy and the Benjamin Shapiro Award for his research on the early and noninvasive diagnosis of brain disorders.​

Sleep Medicine, Stanford Sleep Medicine Center, CA, USA
Atlantic Fellow for Equity in Brain Health, Global Brain Health Institute, University of California San Francisco, CA, USA
Behavioral Neurology and Neuropsychiatry, University of California San Francisco, CA, USA
Neurology, University of Minnesota, MN, USA
Internship, University of Minnesota, MN, USA
MD & PhD, National and Kapodistrian University of Athens, Greece

Clinical Board Certifications​

Sleep Medicine, American Board of Psychiatry and Neurology​

Behavioral Neurology and Neuropsychiatry, United Council of Neurological Subspecialties ​

Neurology, American Board of Psychiatry and Neurology​


  1. Georgopoulos AP, Karageorgiou E, Leuthold AC, Lewis SM, Lynch JK, Alonso AA, Aslam Z, Carpenter AF, Georgopoulos A, Hemmy LS, Koutlas IG, Langheim FJP, McCarten JR, McPherson SE, Pardo JV, Pardo PJ, Parry GJ, Rottunda SJ, Segal BM, Sponheim SR, Stanwyck JJ, Stephane M, Westermeyer JJ. Synchronous neural interactions assessed by magnetoencephalography: A functional biomarker for brain disorders. Journal of Neural Engineering 2007 Dec; 4(4): 349-55 PMID: 18057502​
  2. Georgopoulos AP and Karageorgiou E. Neurostatistics: Applications, challenges and expectations. Statistics in Medicine 2008 Feb; 27(3): 407-17 PMID: 18050155​
  3. Karageorgiou E, Koutlas IG, Alonso AA, Leuthold AC, Lewis SM, Georgopoulos AP. Cortical processing of tactile stimuli applied in quick succession across the fingertips: Temporal evolution of dipole sources revealed by magnetoencephalography. Experimental Brain Research 2008 Aug; 189(3): 311-21 PMID: 18512051​
  4. Karageorgiou E, Schulz SC, Gollub RL, Andreasen NC, Ho BC, Lauriello J, Calhoun VD, Bockholt HJ, Sponheim SR, Georgopoulos AP. Neuropsychological testing and structural magnetic resonance imaging as diagnostic biomarkers early in the course of schizophrenia and related psychoses. Neuroinformatics. 2011 Dec; 9(4):321-33 PMID: 21246418​
  5. Karageorgiou E. The logic of exploratory and confirmatory data analysis. Cognitive Critique 2011 Winter; 3: 35-48​
  6. Karageorgiou E, Lewis SM, McCarten JR, Leuthold AC, Hemmy LS, McPherson SE, Rottunda SJ, Rubins DM, Georgopoulos AP. Canonical correlation analysis of synchronous neural interactions and cognitive deficits in Alzheimer’s dementia. Journal of Neural Engineering 2012; 9(5):056003 Epub 2012 Aug 7 PMID: 22871558​
  7. Karageorgiou E, Schwab DJ, Ezzeddine MA. FLAIR with contrast linked to better correlation with stroke symptoms than diffusion-weighted imaging in a patient: detecting hyperintense acute reperfusion injury marker and cortical enhancement. Cerebrovascular Diseases 2012; 34(4):326–327 PMID: 23147031​
  8. Karageorgiou E and Miller BL. Frontotemporal lobar degeneration: a clinical approach. Seminars in Neurology 2014; 34(2):189-201 PMID: 24963678​
  9. Karageorgiou E. Neglect and extinction in kinesthesia and thesesthesia: understanding proprioceptive inattention. Neurocase 2016;22(2):145-53 PMID: 26275162​
  10. Karageorgiou E, Naasan G, Pleasure SJ, Alexandrescu S, Tammewar G, Gelfand JM, Miller BL, Rabinovici GD, Grinberg LT. Focal cerebral amyloid-β angiopathy: A distinct clinicopathological presentation. Neurology Clinical Practice 2017;7(5):444-448 PMID: 29620074​
  11. Karageorgiou E and Vossel KA. Brain rhythm attractor breakdown in Alzheimer’s disease: Functional and pathologic implications. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 2017;13(9):1054-1067 PMID: 28302453​
  12. Karageorgiou E, Walsh CM, Yaffe K, Neylan TC, Miller BL. Sleep Disorders and Dementia: From Basic Mechanisms to Clinical Decisions. Psychiatric Annals 2017;47(5):227-238​
  13. Beagle AJ, Darwish SM, Ranasinghe KG, La AL, Karageorgiou E, Vossel KA. Relative Incidence of Seizures and Myoclonus in Alzheimer's Disease, Dementia with Lewy Bodies, and Frontotemporal Dementia. Journal of Alzheimer’s Disease 2017;60(1):211-223 PMID: 28826176​
  14. Walsh CM, Ruoff L, Walker K, Emery A, Varbel J, Karageorgiou E, Luong PN, Mance I, Heuer HW, Boxer AL, Grinberg LT, Kramer JH, Miller BL, Neylan TC. Sleepless Night and Day, the Plight of Progressive Supranuclear Palsy. Sleep 2017;40(11). doi: 10.1093/sleep/zsx154. PMID 29029214​
  15. Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD. Neuroimaging in Dementia. Seminars in Neurology. 2017;37(5):510-537. PMID: 29207412​
  16. La AL, Walsh CM, Neylan TC, Vossel KA, Yaffe K, Krystal AD, Miller BL, Karageorgiou E. Long-Term Trazodone Use and Cognition: A Potential Therapeutic Role for Slow-Wave Sleep Enhancers. J Alzheimers Dis. 2019;67(3):911-921. doi: 10.3233/JAD-181145. PMID: 30689583​
  17. Sexton CE, Sykara K, Karageorgiou E, Zitzer J,Talita R, Yaffe K, Leng Y. Connections between insomnia and Cognitive Ageing. Neurosci Bull. 2020; 36(1):77-84 PMID: 31222500​